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Is intrinsic asthma synonymous with infection?
Clin Exp Allergy. 2009 Sep;39(9):1324-9
Authors: Dahlberg PE, Busse WW
Rackemann described the ‘intrinsic asthma’ population over 50 years ago as a unique subgroup that was characterized by onset of progressive loss of lung function beginning later in life, possibly after a respiratory infection. It has also been associated with a female predominance, aspirin-sensitive bronchospasm, and nasal polyposis. While the aetiology is not understood, we propose that persistent respiratory infections play a central role in the development of intrinsic asthma.
PMID: 19638039 [PubMed - indexed for MEDLINE]